Compile Data Set for Download or QSAR
maximum 50k data
Found 49 from Howard Hughes Medical Institute
TargetHistone deacetylase 2(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM50342750(CHEMBL1771484 | N,8-dihydroxy-8-(2-(4-(prop-2-ynyl...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of full length HDAC2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM50342750(CHEMBL1771484 | N,8-dihydroxy-8-(2-(4-(prop-2-ynyl...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of full length HDAC3/NCoR2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM50342752(3-(2-(3-(((R)-5,12-dioxo-2-phenyl-1-oxa-4-azacyclo...)
Affinity DataIC50:  23nMAssay Description:Inhibition of full length HDAC8 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM50342751(CHEMBL1771485 | N-hydroxy-3-(2-(4-(prop-2-ynyloxy)...)
Affinity DataIC50:  29nMAssay Description:Inhibition of full length HDAC8 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  34nMAssay Description:Inhibition of full length HDAC3/NCoR2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM50342749(3-(2-benzylidenehydrazinecarbonyl)-N-hydroxybenzam...)
Affinity DataIC50:  52nMAssay Description:Inhibition of full length HDAC8 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  66nMAssay Description:Inhibition of full length HDAC2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM50342753(3-(2-(3-(((S)-5,12-dioxo-2-phenyl-1-oxa-4-azacyclo...)
Affinity DataIC50:  110nMAssay Description:Inhibition of full length HDAC8 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM50342750(CHEMBL1771484 | N,8-dihydroxy-8-(2-(4-(prop-2-ynyl...)
Affinity DataIC50:  290nMAssay Description:Inhibition of full length HDAC8 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of full length HDAC8 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM50342752(3-(2-(3-(((R)-5,12-dioxo-2-phenyl-1-oxa-4-azacyclo...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of full length HDAC2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM50342753(3-(2-(3-(((S)-5,12-dioxo-2-phenyl-1-oxa-4-azacyclo...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of full length HDAC2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27872(N-(diphenylmethyl)-3-hydroxy-4-sulfanylidene-4H-py...)
Affinity DataIC50:  5.00E+3nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM50342751(CHEMBL1771485 | N-hydroxy-3-(2-(4-(prop-2-ynyloxy)...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of full length HDAC3/NCoR2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM50342751(CHEMBL1771485 | N-hydroxy-3-(2-(4-(prop-2-ynyloxy)...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of full length HDAC2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27874(3-hydroxy-N-[(3-methoxyphenyl)methyl]-4-sulfanylid...)
Affinity DataIC50:  6.60E+3nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27875(N-benzyl-3-hydroxy-4-sulfanylidene-4H-pyran-2-carb...)
Affinity DataIC50:  7.90E+3nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27869(3-hydroxy-N-[(4-phenylphenyl)methyl]-4-sulfanylide...)
Affinity DataIC50:  8.30E+3nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27873(3-hydroxy-N-[(2-methoxyphenyl)methyl]-4-sulfanylid...)
Affinity DataIC50:  8.70E+3nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27870(N-[(4-fluorophenyl)methyl]-3-hydroxy-4-sulfanylide...)
Affinity DataIC50:  9.20E+3nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27871(3-hydroxy-N-[(4-methoxyphenyl)methyl]-4-sulfanylid...)
Affinity DataIC50:  1.06E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27876(N-ethyl-3-hydroxy-4-sulfanylidene-4H-pyran-2-carbo...)
Affinity DataIC50:  1.14E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27859(3-hydroxy-N-[(4-phenylphenyl)methyl]-4-sulfanylide...)
Affinity DataIC50:  1.32E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27862(N-(diphenylmethyl)-3-hydroxy-4-sulfanylidene-4H-py...)
Affinity DataIC50:  1.41E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM50342753(3-(2-(3-(((S)-5,12-dioxo-2-phenyl-1-oxa-4-azacyclo...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of full length HDAC3/NCoR2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM50342752(3-(2-(3-(((R)-5,12-dioxo-2-phenyl-1-oxa-4-azacyclo...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of full length HDAC3/NCoR2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM50342749(3-(2-benzylidenehydrazinecarbonyl)-N-hydroxybenzam...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of full length HDAC3/NCoR2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM50342749(3-(2-benzylidenehydrazinecarbonyl)-N-hydroxybenzam...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of full length HDAC2 assessed as 7-amino-4-methylcoumarin release from fluorophore conjugated substrate after 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27860(N-[(4-fluorophenyl)methyl]-3-hydroxy-4-sulfanylide...)
Affinity DataIC50:  2.92E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27863(3-hydroxy-N-[(2-methoxyphenyl)methyl]-4-sulfanylid...)
Affinity DataIC50:  3.35E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27864(3-hydroxy-N-[(3-methoxyphenyl)methyl]-4-sulfanylid...)
Affinity DataIC50:  3.74E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27867(1-hydroxy-N-[(4-phenylphenyl)methyl]-6-sulfanylide...)
Affinity DataIC50: >5.00E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27861(3-hydroxy-N-[(4-methoxyphenyl)methyl]-4-sulfanylid...)
Affinity DataIC50:  5.04E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27866(N-ethyl-3-hydroxy-4-sulfanylidene-4H-pyran-2-carbo...)
Affinity DataIC50:  7.25E+4nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27868(N-[(4-fluorophenyl)methyl]-1-hydroxy-6-sulfanylide...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27865(N-benzyl-3-hydroxy-4-sulfanylidene-4H-pyran-2-carb...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27858(N-[(4-fluorophenyl)methyl]-1-hydroxy-6-oxo-1,6-dih...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27857(1-hydroxy-6-oxo-N-[(4-phenylphenyl)methyl]-1,6-dih...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27856(N-ethyl-3-hydroxy-4-oxo-4H-pyran-2-carboxamide | h...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27855(N-benzyl-3-hydroxy-4-oxo-4H-pyran-2-carboxamide | ...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27854(3-hydroxy-N-[(3-methoxyphenyl)methyl]-4-oxo-4H-pyr...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27853(3-hydroxy-N-[(2-methoxyphenyl)methyl]-4-oxo-4H-pyr...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27852(N-(diphenylmethyl)-3-hydroxy-4-oxo-4H-pyran-2-carb...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27851(3-hydroxy-N-[(4-methoxyphenyl)methyl]-4-oxo-4H-pyr...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27849(3-hydroxy-4-oxo-N-[(4-phenylphenyl)methyl]-4H-pyra...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Howard Hughes Medical Institute

LigandPNGBDBM27850(N-[(4-fluorophenyl)methyl]-3-hydroxy-4-oxo-4H-pyra...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained fluorogenic peptide substrate, LF, and small-molecule i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM29135(CHEMBL11608 | cid_5610 | p-Tyramine | tyramine)
Affinity DataEC50:  2.60E+4nMAssay Description:Activity at SER3 receptor expressed in HEK293 cells assessed as increase in calcium by calcium imaging assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM36022((+/-)-octopamine | Octopamine,(+/-))
Affinity DataEC50:  24nMAssay Description:Activity at SER3 receptor expressed in HEK293 cells assessed as increase in calcium by calcium imaging assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Howard Hughes Medical Institute

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataEC50:  100nMAssay Description:Activity at SER4 receptor expressed in HEK293 cells assessed as increase in calcium by calcium imaging assayMore data for this Ligand-Target Pair